Yes. After the programming of a Casambi network/system has been fully completed via the Casambi app, the network can be fully automated to be used without the Casambi app, by using Timers, Casambi enabled switches and sensors, and the Smart Switching function (for devices that support this feature).
Information on Smart Switching can be found here: https://support.casambi.com/support/solutions/articles/12000021627-smart-switching